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PRODID:-//Microsoft Corporation//Outlook MIMEDIR//EN
VERSION:2.0
BEGIN:VEVENT
DTSTART:20151118T163000Z
DTEND:20151118T180000Z
LOCATION:Ballroom E
DESCRIPTION;ENCODING=QUOTED-PRINTABLE:ABSTRACT: Retroviruses are pathogens characterized by their ability to=0Aincorporate viral DNA into a host cell's genome.  Retroviruses like=0ARous Sarcoma Virus (RSV) infect cells during mitosis, when the=0Achromatin is exposed to the cytoplasm. Conversely, the genus of=0Alentiviruses, like the human immunodeficiency virus (HIV), have=0Aevolved to infect non-dividing cells. Despite=0Ainfecting cells at different stages of their life cycles, RSV and HIV=0Ashare a similar late stage replication cycle that is highly dependent=0Aon the group actin polyprotein precursor (Gag), which contains the=0Amatrix (MA), capsid (CA) and nucleocapsid (NC) proteins. Both HIV's CA=0Aand Gag are considered unexploited targets for pharmaceutical=0Aintervention. We describe the techniques that were used to build,=0Asimulate, analyze and visualize the structures of both Gag and CA, as=0Awell as we discuss scientific visualization needs that spurred=0Adevelopment of an interactive GPU-accelerated ray tracing engine and=0Athe use of remote visualization technologies.
SUMMARY:Chemical Visualization of Human Pathogens : The Retroviral Capsids
PRIORITY:3
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