Adapting Genome-Wide Association Workflows for HPC Processing at Pawsey

Authors: Jindan (Charlene) Yang (Pawsey Supercomputing Center), Christopher Harris (Pawsey Supercomputing Center), Sylvia Young (The University of Western Australia), Grant Morahan (The University of Western Australia)

Abstract: As part of Bioinformatics Petascale Pioneers Program at Pawsey Supercomputing Centre, this project adapts a number of genome-wide association workflows to a unique Cray supercomputing environment, transforms the performance of these workflows and significantly boosts the research lifecycle. Pairwise and third order gene-gene interaction studies are sped up by hundreds of times through massive parallelization and GPU computing, laying the ground for larger datasets and higher order analysis in the future.

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